A pneumatic or hydraulic cylinder provides the activating force. The rugged construction provides repetitive production operations but at a cost low enough for short run jobs. These clamps also have the desirable safety feature of being mechanically locked (when fully closed) so that even a total loss of pressure will not cause them to cycle. All these clamps are self-contained. They simply need to be mounted and attached to air or hydraulic lines. Sensors for end position sensing allow the clamps to be used in automated production.